Subclinical hypothyroidism, depression and cognitive impairment: experience at a Lambayeque elderly center

Authors

  • Carol Gonzales Gonzales Escuela de Medicina, Universidad Santo Toribio de Mogrovejo, Chiclayo, Perú.
  • Fátima Deza Becerra Escuela de Medicina, Universidad Santo Toribio de Mogrovejo, Chiclayo, Perú.
  • Franco León Jiménez Escuela de Medicina, Universidad Santo Toribio de Mogrovejo, Chiclayo, Perú.
  • Jaquelyn Poma Ortiz Escuela de Medicina, Universidad Santo Toribio de Mogrovejo, Chiclayo, Perú.

DOI:

https://doi.org/10.15381/anales.v75i4.10849

Keywords:

Hypothyroidism, depression, mild cognitive impairment

Abstract

Introduction: There are few studies on subclinical hypothyroidism in the elderly. Objectives: To determine the frequency of subclinical hypothyroidism, depression and cognitive impairment, and explore their association in elderly patients. Design: Descriptive, crosssectional study. Scenario: EsSalud seniors’ center, Lambayeque, Peru. Methods: In 2012 and 2014 TSH and T4L were determined by ELISA in 84 elderly patients. Depression was assessed through a reduced Yesavage test and cognitive impairment by the mini mental test. Frequencies and percentages were determined and prevalence ratios with 95% confidence intervals were estimated using Epidat v3.1. Main outcome measures: Subclinical hypothyroidism, depression and cognitive impairment and their association. Results: Sixtyfive women (77%) and 19 men (23%) were included. Subclinical hypothyroidism was found in 11 older adults (13.1%), depression in 36 (42.9%) and cognitive impairment in 11 (13.1%). No association between subclinical hypothyroidism and depression (PR: 0.85, CI95% [0.39-1.85], p: 0.677) or subclinical hypothyroidism and cognitive impairment (RP: 2.48, CI95% [0.77-7.98], p: 0.1349) were found. Conclusions: There was a high frequency of subclinical hypothyroidism, depression, and cognitive impairment in the elderlies studied. There was no association between subclinical hypothyroidism and depression or cognitive impairment.

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Published

2014-12-31

Issue

Vol. 75 No. 4 (2014)

Section

Original Breve

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Copyright (c) 2014 Carol Gonzales Gonzales, Fátima Deza Becerra, Franco León Jiménez, Jaquelyn Poma Ortiz

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How to Cite

1.
Gonzales Gonzales C, Deza Becerra F, León Jiménez F, Poma Ortiz J. Subclinical hypothyroidism, depression and cognitive impairment: experience at a Lambayeque elderly center. An Fac med [Internet]. 2014 Dec. 31 [cited 2024 Jul. 17];75(4):327-30. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/10849