Development a quantitative method for the determination of misoprostol acid in human serum

Authors

  • Luis A. López Ministerio Público, Instituto de Medicina Legal, Laboratorio de Toxicología. Perú.

DOI:

https://doi.org/10.15381/ci.v19i2.13633

Keywords:

Misoprostol acid, serum samples, liquid chromatography, metabolite, solid phase extraction

Abstract

Was made an experimental study with longitudinal design to develop a qualitative and quantitative method to determine misoprostol ester through its metabolite misoprostol acid in serum samples. An ultraperformance liquid chromatograph equipment with a mass-mass detector (UPLC MS-MS) was used, obtaining peaks at 2,2 minutes of chromatographic running and concentrations between 3,1 and 18,4 ppb.

Downloads

Published

2017-08-02

Issue

Section

Artículos Originales

How to Cite

1.
López LA. Development a quantitative method for the determination of misoprostol acid in human serum. Ciencia e investigación [Internet]. 2017 Aug. 2 [cited 2024 Jul. 17];19(2):79-83. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/13633