Tirotropina and its correlation with cholesterol and triglycerids in healthy patients and with subclinical thyroid dysfunction
DOI:
https://doi.org/10.15381/ci.v23i1.18738Keywords:
Thyrotropin, cholesterol, triglycerides, subclinical thyroid dysfunctionAbstract
Objective: To correlate the levels of thyrotropin with the levels of cholesterol and serum triglycerides in 250 healthy subjects and patients with subclinical thyroid dysfunction with a minimum fasting of 8 hours. Methodology: Analytical methods: total cholesterol, triglycerides: Enzyme-colorimetric and Thyrotropin: ELISA immunoenzymatic. Results: Thyrotropin was found in healthy subjects 88,68% in men and 89,34% in women, in patients with hyper thyroid dysfunction 1,89% for men and 1,52% for women, as well as hypo 9,43% for men and 9,14% for women. Cholesterol in healthy subjects for men is 49,06% and in women 67,01%; in patients with hyper thyroid dysfunction 50,94% for men and 32,99% for women. Triglycerides in healthy subjects 69,81% in men and 62,44% in women, in patients with hyper thyroid dysfunction 30,19% for men and 37,56% in women. Conclusions: A correlation was found between thyrotropin and cholesterol (p <0,05), this is due to an increase in the number of low-density lipoprotein liver receptors (LDL-col), which accelerates its clearance, was not found correlation between thyrotropin and triglycerides (p> 0,05), cholesterol concentrations are high in subjects with hypothyroidism.
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Copyright (c) 2020 Enrique León, Juan Parreño, Anselma Pardo, Gloria Gordillo, Gustavo Guerra, Mario Carhuapoma, Luz Hernández, José Ortiz, Pedro Saenz, Gabriela Solano, Gladys Moscoso, Dina Medina, Mayra Juan de Dios, Lucero Arias, María Salazar, Ana Guerra, Edy Pérez
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