Multidrug resistant tuberculosis in a Marginal Urban Hospital in Lima 2006-2008

Authors

  • Víctor Crispín P. Centro Materno Infantil M Grau DISA IV Lima Este. Instituto de Investigaciones en Química Biológica, Microbiología y Biotecnología “Marco Antonio Garrido Malo” Facultad de Farmacia y Bioquímica - Universidad Nacional Mayor de San Marcos, Lima, Perú.
  • Mirtha Roque A. Instituto de Investigaciones en Química Biológica, Microbiología y Biotecnología “Marco Antonio Garrido Malo” Facultad de Farmacia y Bioquímica - Universidad Nacional Mayor de San Marcos, Lima, Perú.
  • María E E. Salazar S. Instituto de Investigaciones en Química Biológica, Microbiología y Biotecnología “Marco Antonio Garrido Malo” Facultad de Farmacia y Bioquímica - Universidad Nacional Mayor de San Marcos, Lima, Perú.
  • Julio R. Ruiz Q. Instituto de Investigaciones en Química Biológica, Microbiología y Biotecnología “Marco Antonio Garrido Malo” Facultad de Farmacia y Bioquímica - Universidad Nacional Mayor de San Marcos, Lima, Perú.

DOI:

https://doi.org/10.15381/ci.v14i1.3236

Keywords:

MDR-Tuberculosis, bacterial resistance, resistance patterns.

Abstract

Tuberculosis is a public health problem in the world and Peru, aggravated by multidrug (MDR-TB) and extensively resistant (XDR-TB) forms. The objetives were to describe the resistance to tuberculosis drugs and risk factors to acquire MDR-TB in a marginal urban hospital of Lima, since 2006 to 2008. It is a reported cases studyand was undertaken in Huaycán Hospital. The data collected were acquired from the routine reports of the National Control Program and clinical history. A total of 61 cases of MDR-TB, one of XDR-TB and 7 cases of mono resistant tuberculosis were evaluated; 38 were men (55%) and 31 women (45%). The more affected age group were 15 to 34 years with 55 cases (79,6%). The more frecuent risk factors founded to acquire MDR-TB were: suspicion of failure (FS1, 34 cases, 49%) and failure of treatment one scheme (F1, 14 cases, 20%), and to have had contact with MDR-TB patients (MDR-TB-C, 12 cases, 17%). 76% of cases were resistant from 2 to 5 drugs and 13% from 6 to 9 drugs. There were 32 different resistant patterns to drugs. All cases were treated with individualizad schemes, in 41 cases the treatment was successful (59.4%), 16 cases abandoned the treatment (23,2%) and 6 died (8,7%). In conclusion MDR-TB affect young people, the suspicion of failure and failure of treatment and have been in contact with MDR-TB patiens, were the more frecuent risk factors.

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Published

2011-06-13

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Artículos Originales

How to Cite

1.
Crispín P. V, Roque A. M, Salazar S. MEE, Ruiz Q. JR. Multidrug resistant tuberculosis in a Marginal Urban Hospital in Lima 2006-2008. Ciencia e investigación [Internet]. 2011 Jun. 13 [cited 2024 Jul. 17];14(1):36-8. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/3236