COMPARISON BETWEEN THE DIRECT METHOD AND THE FRIEDEWALD FORMULA TO MEASURE LEVELS OF LDL CHOLESTEROL IN DOGS

Authors

  • José Henry Osorio Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia
  • Yirly Johanna Suárez Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia
  • Jazmín Vinasco Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia

DOI:

https://doi.org/10.15381/rivep.v25i4.10801

Keywords:

LDL cholesterol, canine, direct method, friedewald method

Abstract

The aim of this study was to compare the Direct method and the Friedewald formula method for the determination of LDL cholesterol in dogs. Blood samples were collected in 185 fasted dogs without sex restriction. Serum was extracted and levels of LDL cholesterol were determined by the two methods. The mean, standard deviation, and minimum and maximum values by the Direct method were 49.2 ± 16.7, 14.6 and 96.0 mg/dl, respectively, and by the Friedewald method were 65.2 ± 31.5, 4.6 and 184.2 mg/dl, respectively, with significant difference between the methods (p<0.05). The Direct method is recommended for determining LDL cholesterol levels in dogs.

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Author Biographies

  • José Henry Osorio, Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia
  • Yirly Johanna Suárez, Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia
  • Jazmín Vinasco, Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia

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Published

2014-12-30

Issue

Vol. 25 No. 4 (2014)

Section

Artículos Primarios

License

Copyright (c) 2014 José Henry Osorio, Yirly Johanna Suárez, Jazmín Vinasco

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

AUTHORS RETAIN THEIR RIGHTS:

a. Authors retain their trade mark rights and patent, and also on any process or procedure described in the article.

b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Revista de Investigaciones Veterinarias del Perú (RIVEP).

c. Authors retain theirs right to make a subsequent publication of their work, to use the article or any part thereof (eg a compilation of his papers, lecture notes, thesis, or a book), always indicating the source of publication (the originator of the work, journal, volume, number and date).

How to Cite

Osorio, J. H., Suárez, Y. J., & Vinasco, J. (2014). COMPARISON BETWEEN THE DIRECT METHOD AND THE FRIEDEWALD FORMULA TO MEASURE LEVELS OF LDL CHOLESTEROL IN DOGS. Revista De Investigaciones Veterinarias Del Perú, 25(4), 504-507. https://doi.org/10.15381/rivep.v25i4.10801