Development of islets of Langerhans in pancreas of neonatal alpacas

Authors

  • José Rodríguez G. Estación Experimental El Mantaro, Centro de Investigaciones IVITA, Universidad Nacional Mayor de San Marcos, Junín
  • Juan Espinoza B. Laboratorio de Farmacología y Toxicología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima
  • Gabriela Rojas Z. Laboratorio de Fisiología Animal, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima
  • Boris Lira M. Laboratorio de Fisiología Animal, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima
  • María Vásquez C. Laboratorio de Fisiología Animal, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima
  • Bernardo López-Torres Laboratorio de Farmacología y Toxicología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima
  • César Caro M. Laboratorio de Patología, Servicio Nacional de Sanidad Agraria (SENASA), Lima

DOI:

https://doi.org/10.15381/rivep.v26i3.11171

Keywords:

endocrine pancreas, baby alpaca, neonatal development

Abstract

The aim of this study was to determine the postnatal development of Islets of Langerhans (IL) in alpacas of 0 to 45 days of age. The animals were divided in nine age groups with range of five days. The mumber of IL varied from 3.03 to 4.46 in 10x fields (with an ocular of 10x), the IL diameter varied from 67.89 to 72.55 μm, the number of β cells in the IL from 23.79 to 47.08 and other cells from 18.15 to 39.93. Moreover, the insulin receptor and the transport protein GLUT-2 were observed by immunohistochemistry on the first day of life. It is concluded that the number and size of IL increased with age (p<0.05) while β cells do not show the same trend.

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Published

2015-09-14

Issue

Section

Artículos Primarios

How to Cite

Rodríguez G., J., Espinoza B., J., Rojas Z., G., Lira M., B., Vásquez C., M., López-Torres, B., & Caro M., C. (2015). Development of islets of Langerhans in pancreas of neonatal alpacas. Revista De Investigaciones Veterinarias Del Perú, 26(3), 381-388. https://doi.org/10.15381/rivep.v26i3.11171