Toxic effect of macrocysts of Sarcocystis aucheniae H. Wild in house mice

Authors

  • Víctor Carhuapoma D. Instituto de Investigación y Producción Científica, Huancavelica
  • Nicasio Valencia M. E.A.P. Zootecnia, Universidad Nacional de Huancavelica, Huancavelica
  • Víctor Saches A. Instituto de Investigación y Producción Científica, Huancavelica

DOI:

https://doi.org/10.15381/rivep.v27i3.11988

Keywords:

Sarcocystis, macrocystis, inoculum, mouse, lethality

Abstract

The aim of the study was to determine the toxicity of lysate macrocysts inoculum of Sarcocystis aucheniae (LMSA) in house mice (n=36) at concentrations of 5 and 10% (0, 50 and 100 mg of protein per gram of body weight) in doses of 0.5 and 1.0 ml. Rectal temperature, respiratory rate and survival rate plus histopathological changes in liver, kidney, heart, and lung were evaluated. All treated mice died within 4 to 20 hours after inoculation, showing hypothermia, dyspnea and bradypnea. The kidney and liver were most affected organs, showing severe hyperemia, tissue degeneration and hyperplasia. The mice in the control group showed no visible abnormalities or death. The results showed toxicity and lethality due to the lysate macrocysts inoculum of Sarcocystis aucheniae in house mice.

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Published

2016-10-01

Issue

Vol. 27 No. 3 (2016)

Section

Artículos Primarios

License

Copyright (c) 2016 Víctor Carhuapoma D., Nicasio Valencia M., Víctor Saches A.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Revista de Investigaciones Veterinarias del Perú (RIVEP).

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How to Cite

Carhuapoma D., V., Valencia M., N., & Saches A., V. (2016). Toxic effect of macrocysts of Sarcocystis aucheniae H. Wild in house mice. Revista De Investigaciones Veterinarias Del Perú, 27(3), 589-594. https://doi.org/10.15381/rivep.v27i3.11988