CLORURO DE BENZALCONIO EN EL TRATAMIENTO DE LA DERMATOMICOSIS CAUSADA POR Trichophyton sp. EN EL CUY (Cavia cobayo)

Authors

  • Sandra Bezada Q. Práctica privada.
  • Norma Noé M. Laboratorio de Medicina Veterinaria Preventiva, FMV-UNMSM
  • Vilma Béjar C. Instituto de Medicina Tropical “DAC”, UNMSM
  • Juan Mascari G. Instituto Nacional de Investigación Agraria (INIA)

DOI:

https://doi.org/10.15381/rivep.v15i1.1556

Keywords:

benzalkonium chloride, dermatomycosis, guinea pig, treatment

Abstract

The efficacy of benzalkonium chloride for the treatment of dermatomicosis caused by Trichophyton sp. in guinea pig (Cavia cobayo) was evaluated in 200 guinea pigs of two months old, that showed typical clinical signs of dermatomicosis. Hair samples and skin grudges were taken for direct exam and for in vitro culture in Dermatophytes Test Medium and Mycobiotic. Skin biopsies for pathobiology were prepared. The guinea pig were divided in groups A and B of 100 animals each. Group A was treated with 0.1% aqueous benzalkonium chloride solution, whereas group B was treated with water as placebo. All samples were positive to media culture by 3rd to 7th day and Trichophyton mentagrophytes was isolated. Sixty percent of the samples were positive to direct exam. Histological study showed mild hyperkeratosis. Healing of lesions and hair growth were observed in all treated guinea pigs by the end of 4th week. The study showed that a single application of 0.1% aqueous benzalkonium chloride solution was effective for topical treatment on guinea pig dermatomycosis.

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Published

2004-07-15

Issue

Vol. 15 No. 1 (2004)

Section

Artículos Primarios

License

Copyright (c) 2004 Sandra Bezada Q., Norma Noé M., Vilma Béjar C., Juan Mascari G.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

AUTHORS RETAIN THEIR RIGHTS:

a. Authors retain their trade mark rights and patent, and also on any process or procedure described in the article.

b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Revista de Investigaciones Veterinarias del Perú (RIVEP).

c. Authors retain theirs right to make a subsequent publication of their work, to use the article or any part thereof (eg a compilation of his papers, lecture notes, thesis, or a book), always indicating the source of publication (the originator of the work, journal, volume, number and date).

How to Cite

Bezada Q., S., Noé M., N., Béjar C., V., & Mascari G., J. (2004). CLORURO DE BENZALCONIO EN EL TRATAMIENTO DE LA DERMATOMICOSIS CAUSADA POR Trichophyton sp. EN EL CUY (Cavia cobayo). Revista De Investigaciones Veterinarias Del Perú, 15(1), 8-12. https://doi.org/10.15381/rivep.v15i1.1556