Efficacy of a vectorized vaccine for the control of Newcastle Disease applied in chicks in the hatchery

Authors

  • Mercedes Sialer G. Laboratorio de Patología Aviar, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Eliana Icochea D’A. Laboratorio de Patología Aviar, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Armando E. González Z. Laboratorio de Epidemiología y Economía Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú

DOI:

https://doi.org/10.15381/rivep.v31i2.17835

Keywords:

Newcastle disease, vectorized vaccine, velogenic strain

Abstract

The present study evaluated the efficacy of a vectorized vaccine against Newcastle disease virus (vENC) applied in the hatchery. Two hundred one-day-old chicks were distributed in four experimental vaccination groups against vENC: T1: Live attenuated vaccine + inactivated vaccine, T2: Live attenuated vaccine, T3: Live attenuated vaccine + vectorized vaccine, T4: Unvaccinated control group. All chicks were also vaccinated against infectious bronchitis, Marek and Gumboro viruses at day 1. The birds were challenged on the day 26 with a highly pathogenic field pathogenic strain. Mortality, post-challenge clinical signs, necropsy lesions and antibody response against vENC were evaluated. Chicks vaccinated with the vENC vectorized vaccine had a lower mortality (2%) compared to birds vaccinated with live attenuated strains (12.5% ​​for T1 and 18.4% for T2 respectively; p<0.05). Likewise, a lower percentage of post-challenge clinical manifestations (p<0.05) and of lesions in organs at necropsy. The results indicate a better protective effect using the vectorized vaccine and its potential use for the control of vENC under field conditions.

 

Downloads

Download data is not yet available.

Downloads

Published

2020-06-20

Issue

Vol. 31 No. 2 (2020)

Section

Artículos Primarios

License

Copyright (c) 2020 Mercedes Sialer G., Eliana Icochea D’A., Armando E. González Z.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

AUTHORS RETAIN THEIR RIGHTS:

a. Authors retain their trade mark rights and patent, and also on any process or procedure described in the article.

b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Revista de Investigaciones Veterinarias del Perú (RIVEP).

c. Authors retain theirs right to make a subsequent publication of their work, to use the article or any part thereof (eg a compilation of his papers, lecture notes, thesis, or a book), always indicating the source of publication (the originator of the work, journal, volume, number and date).

How to Cite

Sialer G., M., Icochea D’A., E., & González Z., A. E. (2020). Efficacy of a vectorized vaccine for the control of Newcastle Disease applied in chicks in the hatchery. Revista De Investigaciones Veterinarias Del Perú, 31(2), e17835. https://doi.org/10.15381/rivep.v31i2.17835