Clinical-biological development of rats fed a semi-purified diet based on egg white

Authors

DOI:

https://doi.org/10.15381/rivep.v32i4.19438

Keywords:

semi purified diet, egg white protein diet, EWP diet, Sprague Dawley, clinicalmetabolic parameters, biological parameters, mineral levels

Abstract

There is a shortage of concentrated feeds for animals in the country and therefore the research focused on developing a diet based on the guidelines of the American Institute of Nutrition (AIN) with endogenous ingredients and testing them in rats in pregnancy, lactation and growth. In Experiment 1, 12 male Sprague Dawley (SD) rats of 5-6 weeks were worked, half of them fed with a control diet and the other half with a non-purified diet based on egg white (EWP) for six weeks. In Experiment 2, 10 pregnant SD rats were subjected to the same diets (control and EWP) to select 14 four-week-old male neonates to continue with the same feeding regimens for five more weeks (7 in control diet and 7 in EWP). In both experiments, an evaluation of clinical-metabolic parameters (body weight, clinical evaluation and metabolic cage study) was carried out. In the second experiment, biological parameters (protein concentration and hematology) were also evaluated. The results show stable clinical-metabolic parameters and normal biological parameters, which allows to conclude that EWP is suitable for the optimal and healthy development of laboratory rats.

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Author Biographies

  • Jesús Rafael del Castillo Salomón, Instituto Venezolano de Investigaciones Científicas

    Laboratory Boss in Molecular Physiology Laboratory on Center for Biophysics and Biochemistry on Venezuelan Institute of Scientific Research.

     
  • Francisco Fernando Herrera Mirabal, Instituto Venezolano de Investigaciones Científicas

    Researcher in Plant Ecophysiology Laboratory on Ecology Center on Venezuelan Institute of Scientific Research.

  • Guillermina Aguiar Guzmán, Instituto Venezolano de Investigaciones Científicas

    Research Associate Professional at the Plant Ecophysiology Laboratory on Ecology Center on Venezuelan Institute for Scientific Research.

     
  • Lusliany Josefina Rondón Verenzuela, Venezuelan Institute for Scientific Research

    Associate Researcher at the Molecular Physiology Laboratory of the Center for Biophysics and Biochemistry ine Venezuelan Institute of Scientific Research

     

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Published

2021-08-24

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Section

Artículos Primarios

How to Cite

González-Infante, G. A., del Castillo Salomón, J. R., Herrera Mirabal, F. F., Aguiar Guzmán, G., Marcano, E., & Rondón Verenzuela, L. J. (2021). Clinical-biological development of rats fed a semi-purified diet based on egg white. Revista De Investigaciones Veterinarias Del Perú, 32(4), e19438. https://doi.org/10.15381/rivep.v32i4.19438