Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report

Authors

  • Lucia del Carmen Favila-Humara CENID Microbiología Animal, Instituto Nacional de Investigaciones Agrícolas Forestales y Pecuarias INIFAP, Colonia Pal Alto, Cuajimalpa
  • Marco Antonio Santillán-Flores CENID Microbiología Animal, Instituto Nacional de Investigaciones Agrícolas Forestales y Pecuarias INIFAP, Colonia Pal Alto, Cuajimalpa
  • María Guadalupe Martínez-Serrano CENID Microbiología Animal, Instituto Nacional de Investigaciones Agrícolas Forestales y Pecuarias INIFAP, Colonia Pal Alto, Cuajimalpa
  • José Francisco Morales-Álvarez CENID Microbiología Animal, Instituto Nacional de Investigaciones Agrícolas Forestales y Pecuarias INIFAP, Colonia Pal Alto, Cuajimalpa

DOI:

https://doi.org/10.15381/rivep.v32i1.19498

Keywords:

bovine tuberculosis, meningoencephalitis, Mycobacterium bovis, PCR

Abstract

A clinical case of tuberculous meningoencephalitis in a 5-month-old Holstein calf that presented nervous symptoms is described. The calf was part of a herd with a 30% prevalence of tuberculosis. The animal was euthanized, and a necropsy was performed. No lesions were found in organs of the thoracic or abdominal cavity. Brain samples were taken for histopathology (hematoxylin-eosin and Zielh Nelsen staining), bacteriology and PCR-MRD1 studies. In the brain, macroscopic inflammatory lesions with congestion and granular appearance were observed in the meninges, as well as fibrous adhesions in the ventral area. Microscopically, inflammatory infiltrate, lymphocytes, macrophages, epithelioid cells, plasma cells and multinucleated giant cells, areas of central necrosis, dystrophic mineralization and acid-fast bacilli were observed. Granulomatous meningoencephalitis due to Mycobacterium bovis was confirmed by bacterial isolation and PCR-MRD1.

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Published

2021-02-26

Issue

Vol. 32 No. 1 (2021)

Section

Comunicaciones

License

Copyright (c) 2021 Lucia del Carmen Favila-Humara, Marco Antonio Santillán-Flores, María Guadalupe Martínez-Serrano, José Francisco Morales-Álvarez

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

AUTHORS RETAIN THEIR RIGHTS:

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b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Revista de Investigaciones Veterinarias del Perú (RIVEP).

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How to Cite

Favila-Humara, L. del C., Santillán-Flores, M. A., Martínez-Serrano, M. G., & Morales-Álvarez, J. F. (2021). Meningoencephalitis caused by Mycobacterium bovis in a calf. Case report. Revista De Investigaciones Veterinarias Del Perú, 32(1), e19498. https://doi.org/10.15381/rivep.v32i1.19498