Detection and expression of retinoic X receptors (RXR) in the jejunal mucosa of baby alpaca (Vicugna pacos)

Authors

  • Alessandra Bocanegra A. Laboratorio de Microbiología y Parasitología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Peru
  • Alberto Manchego S. Laboratorio de Microbiología y Parasitología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Peru https://orcid.org/0000-0002-8199-0418
  • Miguel Rojas M. Laboratorio de Microbiología y Parasitología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Peru
  • Gustavo Murga A. Laboratorio de Microbiología y Parasitología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Peru https://orcid.org/0000-0001-6072-2986
  • Nieves Sandoval C. Laboratorio de Histología, Embriología y Patología Animal, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Peru https://orcid.org/0000-0003-0112-9183

DOI:

https://doi.org/10.15381/rivep.v32i3.20388

Keywords:

X retinoic receptors, RXR, PCR, real time RT PCR, jejunal mucosa, pups, alpaca

Abstract

The present study determined the presence of retinoic X receptor isoforms (RXR) genes in the genome of adult alpacas and their expression in the jejunal mucosa of alpaca offspring. Blood leukocyte samples from five adult alpacas were used to detect the genes of the RXRbeta and RXRgamma isoforms by PCR using specific primers, and to determine the expression of the RXR gene isoforms, 35 jejunum samples from young alpacas were used (1-50 days old), to which the real-time RT-PCR test was performed. The results indicate that the alpacas have encoded the RXRbeta and RXRgamma isoforms in their genome and that they have different levels of expression in the jejunal mucosa of baby alpacas. High expression of RXRgamma and RXRbeta was detected. These results indicate that the RXRgamma and RXRbeta receptors are being expressed in the mucosa of the jejunum of baby alpacas.

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Published

2021-06-23

Issue

Vol. 32 No. 3 (2021)

Section

Artículos Primarios

License

Copyright (c) 2021 Alessandra Bocanegra A., Alberto Manchego S., Miguel Rojas M., Gustavo Murga A., Nieves Sandoval C.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

AUTHORS RETAIN THEIR RIGHTS:

a. Authors retain their trade mark rights and patent, and also on any process or procedure described in the article.

b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Revista de Investigaciones Veterinarias del Perú (RIVEP).

c. Authors retain theirs right to make a subsequent publication of their work, to use the article or any part thereof (eg a compilation of his papers, lecture notes, thesis, or a book), always indicating the source of publication (the originator of the work, journal, volume, number and date).

How to Cite

Bocanegra A., A., Manchego S., A., Rojas M., M., Murga A., G., & Sandoval C., N. (2021). Detection and expression of retinoic X receptors (RXR) in the jejunal mucosa of baby alpaca (Vicugna pacos). Revista De Investigaciones Veterinarias Del Perú, 32(3), e20388. https://doi.org/10.15381/rivep.v32i3.20388