American tripanosomiasis, a new look at its treatment
DOI:
https://doi.org/10.15381/anales.v77i1.11551Keywords:
Chagas Disease, Trypanosomiasis, Therapeutics.Abstract
American trypanosomiasis or Chagas disease is a parasitic infection caused by the flagellate parasite Trypanosoma cruzi, whose main vector is an insect of the Hemiptera class, called triatomine. Chemotherapy, in addition to an appropriate vector control and a rigorous control of transfusions, are the most important strategies for the management of this parasitosis. Currently, the pharmaceutical market only offers nifurtimox and benznidazole as treatment options, and although satisfactory results have been obtained with the use of these drugs in either acute stages of the disease, congenital trypanosomiasis and laboratory accidents, its effectiveness in the chronic phases is significantly smaller. In addition, both drugs produce some side effects that must be taken into account by health workers, before starting the proper management of the disease. The aim of this article is to review the current state of the American trypanosomiasis treatment, in order to summarize the new advances in therapeutics and to introduce their limitations due to adverse effects.Downloads
Published
2016-03-14
Issue
Section
Artículos de Revisión
License
Copyright (c) 2016 Emmanuel Sánchez, María Camila Vélez, Marcos Restrepo, Juan Sebastián Marín, Daniel Gallego
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Those authors who have publications with this magazine accept the following terms:
- Authors will retain their copyrights and guarantee the journal the right of first publication of their work, which will be simultaneously subject to Creative Commons Attribution License that allows third parties to share the work as long as its author and its first publication this magazine are indicated.
- Authors may adopt other non-exclusive licensing agreements for the distribution of the version of the published work (eg, deposit it in an institutional electronic file or publish it in a monographic volume) provided that the initial publication in this magazine is indicated.
- Authors are allowed and recommended to disseminate their work over the Internet (eg: in institutional telematic archives or on their website) before and during the submission process, which It can produce interesting exchanges and increase quotes from the published work. (See El efecto del acceso abierto ).
How to Cite
1.
Sánchez E, Vélez MC, Restrepo M, Marín JS, Gallego D. American tripanosomiasis, a new look at its treatment. An Fac med [Internet]. 2016 Mar. 14 [cited 2024 May 19];77(1):39-44. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/11551