Neurologic manifestations of Zika virus infection

Authors

  • Joseph R. Zunt Departments of Global Health, Neurology, Medicine (Infectious Diseases), and Epidemiology, University of Washington, Seattle, USA

DOI:

https://doi.org/10.15381/anales.v78i1.13027

Keywords:

Zika Virus, Neurologic Manifestations, Central Nervous System Infection, Guillain-Barré Syndrome.

Abstract

Zika virus is a flavivirus transmitted via mosquito bite, blood transfusion, sexual intercourse or from mother-to-child during gestation. Although neurologic complications of Zika virus infection are rare, Guillain-Barré syndrome (GBS) is the most common manifestation and typically develops soon after the initial systemic manifestations of Zika virus infection. This syndrome typically starts in the distal limbs with symmetric sensory abnormalities and progresses to involve weakness and decreased or absent deep tendon reflexes. Severe cases may also involve respiratory and cardiovascular impairment requiring care in an intensive care unit, and ventilator or circulatory support. A review of 166 published cases of GBS associated with Zika virus is notable for lower mortality than seen with sporadic GBS, but limited data regarding long-term outcome. When available, treatment with intravenous IgG (IVIg) or plasmapheresis, can reduce the severity and duration of symptoms.

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Published

2017-05-16

Issue

Vol. 78 No. 1 (2017)

Section

Simposio

License

Copyright (c) 2017 Joseph R. Zunt

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How to Cite

1.
Zunt JR. Neurologic manifestations of Zika virus infection. An Fac med [Internet]. 2017 May 16 [cited 2024 Jul. 17];78(1):83-7. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/13027