Obesity and dyslipoproteinemia

Authors

  • Fausto Garmendia Lorena Doctor en Medicina; Profesor Principal, Departamento de Medicina Humana; Investigador Permanente, Instituto de Investigaciones Clínicas, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú; Academia Nacional de Medicina

DOI:

https://doi.org/10.15381/anales.v78i2.13217

Keywords:

Obesity, Dyslipoproteinemia, Insulin Resistance.

Abstract

The definition, main general causes, quantification and body distribution of obesity are described. A general review of the different blood lipoprotein fractions as well as the procedure for the diagnosis of dyslipoproteinemia is done. Dyslipoproteinemia of obesity is a secondary form of insulin resistance as a result of lowering of lipoprotein lipase activity resulting in increase of triglycerides, decrease of HDL cholesterol, and establishment of the metabolic syndrome. Its pathophysiology and the development of obesity related morbidities are described. Dyslipoproteinemia of obesity is present in both the basal and postprandial status. An attempt is made to estimate the prevalence of dyslipoproteinemia. Treatment is outlined and includes change in lifestyle regarding diet and physical activity, pharmacotherapy, and bariatric surgery, as well as the hypolipidemic treatment.

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Published

2017-07-17

Issue

Vol. 78 No. 2 (2017)

Section

Simposio

License

Copyright (c) 2017 Fausto Garmendia Lorena

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How to Cite

1.
Garmendia Lorena F. Obesity and dyslipoproteinemia. An Fac med [Internet]. 2017 Jul. 17 [cited 2024 Jul. 17];78(2):196-201. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/13217