TREATMENT OF Strongyloides stercoralis WITH IVERMECTIN AND THIABENDAZOLE

Authors

  • Pedro Huapaya Instituto de Medicina Tropical “Daniel A. Carrión”, UNMSM; Departamento Académico de Microbiología Médica, Facultad de Medicina, UNMSM
  • Yrma Espinoza Instituto de Medicina Tropical “Daniel A. Carrión”, UNMSM; Departamento Académico de Microbiología Médica, Facultad de Medicina, UNMSM
  • Alina huiza Instituto de Medicina Tropical “Daniel A. Carrión”, UNMSM; Departamento Académico de Microbiología Médica, Facultad de Medicina, UNMSM
  • Carlos Sevilla Departamento Académico de Microbiología Médica, Facultad de Medicina, UNMSM
  • Herman Vildosóla Instituto de Medicina Tropical “Daniel A. Carrión”, UNMSM

DOI:

https://doi.org/10.15381/anales.v64i2.1433

Keywords:

Strongyloidiasis, ivermectin, Strongyloides stercoralis, anthelmintics.

Abstract

OBJECTIVE: To describe the experience with ivermectin and thiabendazole in patients attended at the Tropical Medicine Institute “Daniel A. Carrión”- UNMSM. MATERIAL AND METHODS: During 2001 and 2002, ivermectin (0,2 mg/kg in single dosis) and thiabendazole (25 mg/kg/3days) were administered to 22 (Group 1) and 20 (Group 2) patients with diagnosis of Strongyloides stercoralis in stools. Controls were performed between 20 and 40 days following treatment. RESULTS: Mean age was 21,8 years (SD 22,6) for group 1 and 33,5 years (SD 14,2) for group 2. There were 12 males (54,5%) in group 1 and 7 (35%) in group 2. Ivermectin was 100% efficient while thiabendazole was 95%; only one case needed a second cycle because of high amount of parasites from the beginning; his next control was negative. Most frequent symptoms were diarrhea (71,4%), abdominal pain (61,9%) and epigastric pain (47,6%); all patients felt better after treatment. Only 2 cases (10%) from group 2 referred light nausea during the first day of treatment that disappeared at the second day. CONCLUSIONS: Both drugs ratify their efficacy and safety for Strongyloides stercoralis treatment making it necessary to have them in the national petitioner.

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Published

2003-06-16

Issue

Vol. 64 No. 2 (2003)

Section

Trabajos originales

License

Copyright (c) 2003 Pedro Huapaya, Yrma Espinoza, Alina huiza, Carlos Sevilla, Herman Vildosóla

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How to Cite

1.
Huapaya P, Espinoza Y, huiza A, Sevilla C, Vildosóla H. TREATMENT OF Strongyloides stercoralis WITH IVERMECTIN AND THIABENDAZOLE. An Fac med [Internet]. 2003 Jun. 16 [cited 2024 Jul. 17];64(2):89-93. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/1433