Consequences of gamma radiation to mice skin

Authors

  • Blanca Chávez Soto Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Lourdes Estrada Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Jorge Hurtado Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Zarela López Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Karina Mancisidor Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Roxana Manco Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • José Paredes Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Jesús Pareja Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Liliana Puycan Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Patricia Ramírez Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

DOI:

https://doi.org/10.15381/anales.v61i4.4370

Keywords:

Radiation, gamma rays, whole-body irradiation, research

Abstract

OBJECTIVE: To determine clinical, biochemical, hematologic and histopathologic effects caused by gamma radiation to mice skin. MATERIAL AND METHODS: Experimental case-control study in 30 albino Balc-10 mice irradiated with fractionated doses, 1.2, 1.8, 3.0, and 3.6 Gy, during 3 sessions with one week interval. RESULTS: Alterations produced with radiation threshold values below 3 Gy were directly related to dose increase, with inverse effect noted above threshold values and remarkable organism response to detrimental action. There was marked reduction in blood cells, mainly lymphocytes. CONCLUSIONS: Gamma irradiation produces various effects that depend on dosage and number of irradiations.
Vol 61, No 4 (2000)

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Published

2000-12-29

Issue

Vol. 61 No. 4 (2000)

Section

Original Breve

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Copyright (c) 2000 Blanca Chávez Soto, Lourdes Estrada, Jorge Hurtado, Zarela López, Karina Mancisidor, Roxana Manco, José Paredes, Jesús Pareja, Liliana Puycan, Patricia Ramírez

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How to Cite

1.
Chávez Soto B, Estrada L, Hurtado J, López Z, Mancisidor K, Manco R, et al. Consequences of gamma radiation to mice skin. An Fac med [Internet]. 2000 Dec. 29 [cited 2024 Jul. 17];61(4):295-8. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/4370