Pathogenesis of parkinsoys disease. Microvascular and neurochemical analysis.

Authors

  • Hernando Rafael Departamento de Neurociencias, Universidad Nacional Autónoma de México, D.F., México

DOI:

https://doi.org/10.15381/anales.v57i4.4894

Keywords:

Substantía nigra, Parkinson disease, Crebral revascularization, Omentum

Abstract

Contrary to the hypothesis of genetic predisposition in the pathogenesis of Parkinson discase as proposed by many researchers, we suggest that an impairment of blood flow to the substantia nigra is the primary pathological process of this disease, not necessarily related to aging. Conclusion: Based ¡n histopathological and neurochenfical findings ¡n dopaminergic neurons, Parkinson's discase is due to a suboptinial and chronic reduction of arteria¡ blood flow to the mesencephalon. Therefore, revascularization of the catecholaminergic nuclei is an aim to be considered.

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Published

1996-12-30

Issue

Vol. 57 No. 4 (1996)

Section

Artículo de Opinión

License

Copyright (c) 1996 Hernando Rafael

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How to Cite

1.
Rafael H. Pathogenesis of parkinsoys disease. Microvascular and neurochemical analysis. An Fac med [Internet]. 1996 Dec. 30 [cited 2024 Aug. 16];57(4):268-73. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/4894