Hepatic involvement in typhoid fever: Biochemical and histopathological study in anicteric patients

Authors

  • Raúl Salazar Departamento de Medicina, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Olga Fajardo Departamento de Medicina, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Ricardo Illescas Departamento de Medicina, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Ricardo Mori Departamento de Medicina, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

DOI:

https://doi.org/10.15381/anales.v56i2.5256

Keywords:

typhoi fever, Salmonella typhi, bone marrow, hepatitis, jaundice

Abstract

Retrospective study of 100 patients with diagnosis of typhoid fever by Salmonella typhi isolation. Main diagnostic procedure was bone marrow culture with 90% positivity. Hepatic involvement occurred in 85% patients, 67 without jaundice and 18 with jaundice. Fifty patients without jaundice had liver biopsy: 50% showed finding compatible with granulomatous hepatitis and 50% with reactional hepatitis. Response to antibiotics was similar in both patients with and without liver involvement.

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Published

1995-12-29

Issue

Vol. 56 No. 2 (1995)

Section

Trabajos originales

License

Copyright (c) 1995 Raúl Salazar, Olga Fajardo, Ricardo Illescas, Ricardo Mori

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How to Cite

1.
Salazar R, Fajardo O, Illescas R, Mori R. Hepatic involvement in typhoid fever: Biochemical and histopathological study in anicteric patients. An Fac med [Internet]. 1995 Dec. 29 [cited 2025 May 24];56(2):30-5. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5256