Study of ceruloplasmin in subjects our midst

Authors

  • Percy Carpio Meléndez Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

DOI:

https://doi.org/10.15381/anales.v51i1-2.5278

Abstract

The physiological role of ceruloplasmin and pathogenesis of its metabolic derangements linked to copper, is still unknown. Wilson's disease is the only disease in man due to a disorder of copper metabolism whose intimate nature is not yet clarified. The usual explanation of the phenomenon (11) observed in the disease is that the patient is unable to synthesize ceruloplasmin when the abnormal gene occurs in the form homociqótica. The increase in copper absorption through the gut and deposit in tissues to toxic levels is said to be secondary to impaired synthesis of ceruloplasmin. This explanation is not consistent, because some patients with Wilson's disease have normal levels of ceruloplasmin or approximately normal.

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Published

1968-06-17

Issue

Vol. 51 No. 1-2 (1968)

Section

Trabajos originales

License

Copyright (c) 1968 Percy Carpio Meléndez

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How to Cite

1.
Carpio Meléndez P. Study of ceruloplasmin in subjects our midst. An Fac med [Internet]. 1968 Jun. 17 [cited 2024 Jul. 17];51(1-2):56-67. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/5278