Constitutional hepatic dysfunction (Gilbert's disease), about eleven cases studied in the Hospital Obrero de Lima

Authors

  • Oswaldo León Navarro Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

DOI:

https://doi.org/10.15381/anales.v45i3-4.6060

Abstract

We report eleven cases of Constitutional Hepatic dysfunction (Gilbert's disease), studied at the Department of Gastroenterology of the Hospital Obrero de Lima. We place this disease in the group of non Chronicles Hemolytic jaundice due to congenital defects in bilirubin metabolism. It is noted, according to the new concepts of bilirubin metabolism, the pathogenic mechanism of this disease is related to deficient activity of glucuronyltransferase, the enzyme responsible for bilirubin conjugation with glucuronic acid.

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Published

1962-12-31

Issue

Vol. 45 No. 3-4 (1962)

Section

Trabajos originales

License

Copyright (c) 1962 Oswaldo León Navarro

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How to Cite

1.
León Navarro O. Constitutional hepatic dysfunction (Gilbert’s disease), about eleven cases studied in the Hospital Obrero de Lima. An Fac med [Internet]. 1962 Dec. 31 [cited 2024 Jul. 4];45(3-4):378-96. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6060