The two hypoprothrombinemic effect of coumarin anticoagulants in our series

Authors

  • Carlos Forno Departamento de Cardiología, Hospital Arzobispo Loayza Lima, Perú
  • Carlos M. Vidurrizaga Departamento de Hematología, Hospital Arzobispo Loayza Lima, Perú
  • Manuel Figallo Instituto de Biología Andina, Facultad de Medicina, Universidad Nacional Mayor de San Marcos Lima, Perú

DOI:

https://doi.org/10.15381/anales.v43i3.6342

Abstract

Since the introduction of coumarin anticoagulants in clinical practice in 1941 (1.2), the end of the experimental works of Karl Paul Link and his group supplement (3.4), its use has spread dramatically. Indeed; the protection offered by these drugs as antagonists of thromboembolic processes confers singular values ​​in all cases, the common denominator is given by those. However, rigorous control required for proper dosage simultaneously ensure optimal antithrombotic effect and bleeding safety, has been perhaps one of the factors which, among us, its use is very restricted.

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Published

1960-09-19

Issue

Vol. 43 No. 3 (1960)

Section

Trabajos originales

License

Copyright (c) 1960 Carlos Forno, Carlos M. Vidurrizaga, Manuel Figallo

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How to Cite

1.
Forno C, Vidurrizaga CM, Figallo M. The two hypoprothrombinemic effect of coumarin anticoagulants in our series. An Fac med [Internet]. 1960 Sep. 19 [cited 2024 Aug. 16];43(3):609-17. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6342