Homocystein levels in menopausal women from Lima, Peru

Authors

  • Marlene Vargas Chávez Escuela de Posgrado, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
  • Ysela Agüero Palacios Instituto de Investigación de Ciencias Matemáticas, UNMSM, Lima, Perú.
  • María M. Soberón Lozano Centro de Investigación Bioquímica y Nutrición, Facultad de Medicina, UNMSM, Lima, Perú.

DOI:

https://doi.org/10.15381/anales.v73i3.866

Keywords:

Homocysteine, premenopause, postmenopause, FSH, estradiol, cardiovascular diseases.

Abstract

Abstract Objectives: To compare serum homocysteine levels according to menopausal status in a group of women. Design: Descriptive study. Setting: Biochemistry and Nutrition Research Center, Faculty of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru. Participants: Women 40 to 60 year-old. Interventions: The menopausal status was determined clinically and by serum FSH and estradiol in 97 women 40 to 60 year-old attended at San Bartolome Hospital, Lima, Peru. Plasma homocysteine was determined by fluorescence polarization immunoanalysis. Main outcome measures: Homocysteine levels. Results: Homocysteine levels were within international referential values (5-15 μmol/L). Postmenopausal women levels were significantly higher compared to premenopausal women levels (p< 0.05). Conclusions: Homocysteine levels are increased in menopausal women and could be considered in cardiovascular disease prediction.

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Published

2012-09-17

Issue

Vol. 73 No. 3 (2012)

Section

Sección Bioquímica y Nutrición

License

Copyright (c) 2012 Marlene Vargas Chávez, Ysela Agüero Palacios, María M. Soberón Lozano

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How to Cite

1.
Vargas Chávez M, Agüero Palacios Y, Soberón Lozano MM. Homocystein levels in menopausal women from Lima, Peru. An Fac med [Internet]. 2012 Sep. 17 [cited 2024 Jul. 17];73(3):211-4. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/866