Primary central nervous system lymphoma in an immunocompetent patient

Authors

  • José Málaga-Zenteno Médico Asistente, Servicio de Hematología, Hospital Nacional Carlos Alberto Seguín Escobedo, EsSalud, Arequipa, Perú.
  • Jersson Alonso Mamani-Quispe Estudiante de Medicina Humana, Centro de Investigación y Estudios Médicos (CIEM), Universidad Católica Santa María, Arequipa, Perú. Sociedad Científica Médico Estudiantil Peruana (SOCIMEP).
  • Mariela Fuentes Fuentes Médico Asistente, Servicio de Hematología, Hospital Nacional Carlos Alberto Seguín Escobedo, EsSalud, Arequipa, Perú.
  • José Alonso Suclla-Velásquez Estudiante de Medicina Humana, Centro de Investigación y Estudios Médicos (CIEM), Universidad Católica Santa María, Arequipa, Perú. Sociedad Científica Médico Estudiantil Peruana (SOCIMEP).
  • Julio Meza Aragón Médico Asistente, Servicio de Neurocirugía, Hospital Nacional Carlos Alberto Seguín Escobedo, EsSalud, Arequipa, Perú.

DOI:

https://doi.org/10.15381/anales.v73i3.872

Keywords:

Lymphoma, central nervous system neoplasm, immunocompetence.

Abstract

Primary central nervous system lymphoma (PCNSL) constitutes 2% of extranodal lymphomas and 0,3%-1,5% of all intracranial neoplasms in immunocompetent patients, being more frequent after the sixth decade of life. We report a case of a 76 year-old man with no antecedents who started his disease with march instability, difficulty to move left side of his body with brachial predominance, holocraneal headache and dizziness. He arrived at emergency with Glasgow 14 and right eyelid ptosis. He had left sided hemiparesis and hypoesthesia with crural predominance and occasional disorientation. Brain computed tomography (CT) showed a contrastenhanced image in the right frontoparietal region with both extra- and intra-cranial components, cerebral edema and middle line deviation. Craniotomy and biopsy of the tumor resulted in diffuse large B cell lymphoma of the central nervous system. The patient was HIV negative. Other primary tumor and metastasis were discarded. He was treated with ‘CHOD/BVAM’ regimen and radiotherapy. He evolved favorably. No tumor was found in the post treatment brain MRI.

Downloads

Published

2012-09-17

Issue

Vol. 73 No. 3 (2012)

Section

Casos clínicos

License

Copyright (c) 2012 José Málaga-Zenteno, Jersson Alonso Mamani-Quispe, Mariela Fuentes Fuentes, José Alonso Suclla-Velásquez, Julio Meza Aragón

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Those authors who have publications with this magazine accept the following terms:

  1. Authors will retain their copyrights and guarantee the journal the right of first publication of their work, which will be simultaneously subject to Creative Commons Attribution License that allows third parties to share the work as long as its author and its first publication this magazine are indicated.
  2. Authors may adopt other non-exclusive licensing agreements for the distribution of the version of the published work (eg, deposit it in an institutional electronic file or publish it in a monographic volume) provided that the initial publication in this magazine is indicated.
  3. Authors are allowed and recommended to disseminate their work over the Internet (eg: in institutional telematic archives or on their website) before and during the submission process, which It can produce interesting exchanges and increase quotes from the published work. (See El efecto del acceso abierto ).

How to Cite

1.
Málaga-Zenteno J, Mamani-Quispe JA, Fuentes Fuentes M, Suclla-Velásquez JA, Meza Aragón J. Primary central nervous system lymphoma in an immunocompetent patient. An Fac med [Internet]. 2012 Sep. 17 [cited 2024 Jul. 17];73(3):245-9. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/872