Aquous Lepidium meyenii Walp (maca) extract and its role as an adaptogen, in an endurance animal model
DOI:
https://doi.org/10.15381/anales.v70i3.936Keywords:
Lepidium, plant extracts, enzyme activation, physical endurance, oxidative stress, lipid peroxidation.Abstract
Introduction: Lepidium meyenii Walp (maca) is a Peruvian Andean root used as food due to its nutritional value and ethnomedical properties, being part of traditional medicine. Objectives: To determine yellow maca aqueous extract adaptogen role on muscle tissue enzymes in an endurance and oxidative stress animal model. Design: Experimental. Setting: Biochemistry and Nutrition Research Center, Faculty of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru. Biological material: Yellow maca aqueous extract and newly weaned male rats. Interventions: Administration of yellow maca aqueous extract in newly weaned male rats divided into four groups: (I) control, (II) 0,4 mg maca/g weight, (III) 0,8 mg maca/g, and (IV) 1,2 mg maca/g. The aqueous extract was administered by orogastric cannula. Weights were controlled. Swimming test was applied after 30 days of treatment. The animals were sacrificed and 10% homogenized muscle was prepared. Main outcome measures: Superoxide dismutase (SOD), catalase (CAT) and lactate dehydrogenase (LDH) enzymes activity; lipid peroxidation (TBARS) was measured as an indicator of the oxidative process. Results: The endurance test performance was respectively: (I) 7,09 min; (II) 11,25 min; (III) 11,27 min; (IV) 12,71 min. Groups I, II, III and IV respective enzymatic activities were: SOD (U/mL) 36,6, 18,2, 17,2 and 18,2; CAT (U/L) 18,6, 16,5, 13,4 and 10,3; and LDH (U/mL) 11,6, 6,5, 6,0 and 5,8. TBARS (umol/g tissue): 5,82, 7,15, 4,11 and 4,06. Conclusions: Yellow maca aqueous extract administration helped body response facing a physically exhausting stressful situation, most probably corresponding to an adaptogen role.Downloads
Published
2009-09-14
Issue
Section
Trabajos originales
License
Copyright (c) 2009 Silvia Suárez, Raquel Oré, Inés Arnao, Luis Rojas, Juan Trabucco
![Creative Commons License](http://i.creativecommons.org/l/by-nc-sa/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Those authors who have publications with this magazine accept the following terms:
- Authors will retain their copyrights and guarantee the journal the right of first publication of their work, which will be simultaneously subject to Creative Commons Attribution License that allows third parties to share the work as long as its author and its first publication this magazine are indicated.
- Authors may adopt other non-exclusive licensing agreements for the distribution of the version of the published work (eg, deposit it in an institutional electronic file or publish it in a monographic volume) provided that the initial publication in this magazine is indicated.
- Authors are allowed and recommended to disseminate their work over the Internet (eg: in institutional telematic archives or on their website) before and during the submission process, which It can produce interesting exchanges and increase quotes from the published work. (See El efecto del acceso abierto ).
How to Cite
1.
Suárez S, Oré R, Arnao I, Rojas L, Trabucco J. Aquous Lepidium meyenii Walp (maca) extract and its role as an adaptogen, in an endurance animal model. An Fac med [Internet]. 2009 Sep. 14 [cited 2024 Jul. 17];70(3):181-5. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/936