Factors associated with primary multidrug-resistant tuberculosis in patients from Callao, Peru
DOI:
https://doi.org/10.15381/anales.v75i3.9775Keywords:
Tuberculosis, multidrug- resistance, risk factors, Peru.Abstract
Introduction: Lima and Callao are high risk areas for tuberculosis active transmission in Peru. Multidrug-resistant tuberculosis represents 5.54% of the new cases of pulmonary tuberculosis (primary MDR-TB) in Lima and Callao. Involved risk factors have not been studied in patients from Callao. Objectives: To determine risk factors for primary MDR-TB in patients attending health care facilities in Callao during 2009-2010. Design: Case-control study. Setting: Health care facilities from Callao. Participants: Twenty nine primary MDR-TB patients and 37 drug-sensitive TB patients were studied through assessment of the Tuberculosis Control Program Registries and healthcare facilities’ clinical records. Interventions: Information was obtained from secondary sources. Odds-ratios were calculated by bivariate analysis. Logistic regression models were used to calculate multivariate odd-ratios. Main outcome measures: Risk factors for primary MDR-TB. Results: Prior contact with a MDR-TB or XDR-TB patient was a significant risk factor (OR: 5.56; 95%CI: 1.05-29.27) in bivariate analysis; the same was found in multivariate analysis (OR: 14.56; 95%CI: 1.52–139.54). Being 40 or more years old was a significant protective factor in multivariate analysis (OR: 0.94; 95% CI: 0.90–0.99). Conclusions: Previous contact with a MDR-TB or XDR-TB patient was a risk factor, and being 40 or more years old was a protective factor for primary MDR-TB in Callao patients studied.
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2014-09-15
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Copyright (c) 2014 Ana Cecilia Ávalos Rodríguez, Fernando Jean Carlos Imán Izquierdo, Manuel André Virú Loza, José Cabrera Rivero, Anthony Edgar Zárate Robles, Mariela Cecibet Meza Monterrey, Brenner Alberto Ñaupari Meza, Wendy Teoana Figueroa Bravo, Mirella Kristal Cajas Socualaya, Hugo Paul Castro Trujillo, Talía Minerva Zapata Susanívar
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Ávalos Rodríguez AC, Imán Izquierdo FJC, Virú Loza MA, Cabrera Rivero J, Zárate Robles AE, Meza Monterrey MC, et al. Factors associated with primary multidrug-resistant tuberculosis in patients from Callao, Peru. An Fac med [Internet]. 2014 Sep. 15 [cited 2024 Jul. 17];75(3):233-6. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/9775
