Effect of a food supplement based on natural supplies and bioactive components of seven roots on sexual behavior in rats

Authors

  • Karin Zamudio Malpartida Amazon Andes Export SAC, Lima – Peru
  • Elizabeth C. Ortega Romero Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica, Departamento Académico de Farmacología, Bromatología y Toxicología. Lima, Peru
  • Gustavo A. Guerra Brizuela Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica,Instituto de Investigación en Química Biológica, Microbiología y Biotecnología, “Marco Antonio Garrido Malo”. Lima, Peru
  • Jorge L. Arroyo Acevedo Universidad Nacional Mayor de San Marcos, Facultad de Medicina, Departamento de Ciencias Dinámicas. Lima, Peru
  • Martin Condorhuamán Figueroa Universidad Nacional Mayor de San Marcos, Facultad de Farmacia y Bioquímica, Instituto de Investigación en Ciencias Farmacéuticas y Recursos Naturales “Juan de Dios Guevara”. Lima, Peru

DOI:

https://doi.org/10.15381/ci.v23i2.19380

Keywords:

Food supplement, plant extract, bioactive components, sexual behavior

Abstract

The present study aimed to determine the effect of a food supplement based on natural inputs and bioactive components of plant species on sexual behavior. It is an experimental, prospective and longitudinal investigation. For the test, 150 albino rats were used: 75 females and 75 males of the Holtzmann breed of 12 weeks of age, with an average weight of 200 to 250 g. (males) and 150 - 200 g. (females). Two products were evaluated: One that contained the extract of the roots of seven plant species at doses of 200 and 400mg / kg and Two that contained the product one plus chestnut flour and Sacha inchi at a dose of 830mg / kg. The trial was carried out for 10 weeks and the evaluations were carried out at the eighth, ninth and tenth weeks (days 1, 7 and 14 respectively). Likewise, the evaluation of the biochemical, hematological, testosterone and prostate-specific antigen (PSA) parameters was carried out. Products One at a dose of 400mg / kg and Two at a dose of 830mg / kg showed a significant effect on sexual behavior compared with the control and standard groups (sildenafil 5mg / kg). There were no changes at the biochemical or hematological level. It is concluded that the tested products had an effect on sexual behavior by increasing libido in male rats, without side effects on biochemical and hematological parameters.

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Published

2020-12-31

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Artículos Originales

How to Cite

1.
Zamudio Malpartida K, Ortega Romero EC, Guerra Brizuela GA, Arroyo Acevedo JL, Condorhuamán Figueroa M. Effect of a food supplement based on natural supplies and bioactive components of seven roots on sexual behavior in rats. Ciencia e investigación [Internet]. 2020 Dec. 31 [cited 2024 Jul. 17];23(2):41-9. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/19380