Antimicrobial and fungicide activity of anthraquinones from Aloe vera L. combined with copper, iron, silver and bismuth cations

Authors

  • Félix E. Saavedra Centro Latinoamericano de Enseñanza e Investigación en Bacteriología Alimentaria - CLEIBA.
  • Benedicta C. López Centro Latinoamericano de Enseñanza e Investigación en Bacteriología Alimentaria - CLEIBA.
  • Victoria J. Yrei Centro Latinoamericano de Enseñanza e Investigación en Bacteriología Alimentaria - CLEIBA.
  • Gallardo C. Gallardo Laboratorio Química Analítica e Instrumentación. Facultad de Química de Ing. Química.
  • Gloria C. Gordillo Instituto de Química Biológica, Microbiología y Biotecnología “Marco Antonio Garrido Malo”.
  • Gloria C. Gordillo Instituto de Química Biológica, Microbiología y Biotecnología “Marco Antonio Garrido Malo”.

DOI:

https://doi.org/10.15381/ci.v15i1.3190

Keywords:

Aloe vera L., anthraquinones, cooper and silver cations, antimicrobial fungicide.

Abstract

This study aimed to evaluate the antimicrobial and fungicidal activity of aqueous and alcoholic macerated from leaves of Aloe vera L., containing anthraquinone derivatives. With this macerated liquids were prepared solutions of CuSO4.5H2O 1,5%, FeCl3 1%, AgNO3 1%, and Bi (NO3)3 1,5%, which were stored in amber glass flasks, hermetically closed for 12 months under refrigeration; a similar batch was kept at 25°C. Antimicrobial and fungicide activities were determined on these preparations using plate excavation method, of USP XXX, against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Aspergillus niger strains. Aqueous solutions of Aloe vera L. showed antimicrobial activity in decreasing order Cu > Ag > Fe and alcoholic solutions in also decreasing order Ag > Cu > Fe. Only copper sulphate aqueous solutions showed fungicidal activity. The preparations preserved under refrigeration, had greater antimicrobial and fungicidal activity than equivalent preparations preserved at room temperature of 25°C.

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Published

2012-06-18

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Artículos Originales

How to Cite

1.
Saavedra FE, López BC, Yrei VJ, Gallardo GC, Gordillo GC, Gordillo GC. Antimicrobial and fungicide activity of anthraquinones from Aloe vera L. combined with copper, iron, silver and bismuth cations. Ciencia e investigación [Internet]. 2012 Jun. 18 [cited 2024 Jul. 17];15(1):30-5. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/3190