Comprobación del efecto cicatrizante de Peperomia scutellaefolia R et P. aspectos botánicos, químicos y farmacológicos

Authors

  • Ruth F. Guillermo Instituto de Investigación en Ciencias Farmacéuticas y Recursos Naturales «Juan de Dios Guevara» Facultad de Farmacia y Bioquímica de la Universidad Nacional Mayor de San Marcos, Lima, Perú.
  • Pablo E. Bonilla R Instituto de Investigación en Ciencias Farmacéuticas y Recursos Naturales «Juan de Dios Guevara» Facultad de Farmacia y Bioquímica de la Universidad Nacional Mayor de San Marcos, Lima, Perú.
  • Jorge L. Arroyo A. Laboratorio de Farmacología Facultad de Medicina de la Universidad Nacional Mayor de San Marcos, Lima, Perú.

DOI:

https://doi.org/10.15381/ci.v8i1.5215

Keywords:

Peperomia scutellaefolia R. et P., wound healing, tensiometric method, flavonoids, spectrophotometry ultraviolet and infrared

Abstract

A description of the morphological external characteristics of Peperomia scutellaefolia R. et P. and some microscope details and the wound healing effect of vegetal specie Peperomia scutellaefolia R. et P. were evaluated and described in this research using tensiometric methods and the results were corroborated with histological studies in order to observe and analyze the histological evolution in each case. Batch Balb C 53 albine mice with 25g of average weight were used and treated with Carbopol 940 gel s with 5%, 10%, 20% and 30% W /W concentrations of this vegetal extract. The results obtained were compared with two groups: the control group (without treatment) and another group treated with a commercial medicament. A better wound healing cffect with Peperomia' s 5% W /W concentration gel was obtained. Flavonoids and fenolic compounds were found and identified by ultraviolet and infrared spectrophotometry and coloration reactions.

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Published

2005-06-13

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Section

Artículos Originales

How to Cite

1.
Guillermo RF, Bonilla R PE, Arroyo A. JL. Comprobación del efecto cicatrizante de Peperomia scutellaefolia R et P. aspectos botánicos, químicos y farmacológicos. Ciencia e investigación [Internet]. 2005 Jun. 13 [cited 2025 Jun. 5];8(1):9-16. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/farma/article/view/5215