Implications of endothelium dysfunction in heart failure

Authors

  • Beatriz Wills Sanín Médica Rural de Cuidado Crítico Fundación Santa Fe de Bogotá, Colombia.
  • Andrés Felipe Buitrago Especialista en Medicina Interna, Cardiología y Epidemiología, Hospital Universitario Fundación Santa Fe de Bogotá, Colombia. Jefe Asociado del Departamento de Medicina Crítica y Cuidado Intensivo, Hospital Universitario Fundación Santa Fe de Bogotá, Colombia

DOI:

https://doi.org/10.15381/anales.v75i4.10857

Keywords:

Endothelium, heart failure, nitric oxide, new agents

Abstract

The role of the endothelium in heart failure has been the focus of intense research, since it has important biologic implications. There are individual differences in the pattern of endothelial dysfunction according to the etiology and severity of heart failure. Endothelial dysfunction is also associated with negative outcomes. We are eagerly waiting for new pharmacological agents targeted specifically to the vascular endothelium. In this review, we aim to provide a critical analysis of the available evidence on the pathological consequences and prognosis of endothelial abnormalities as related to the onset and natural history of heart failure.

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Published

2014-12-31

Issue

Vol. 75 No. 4 (2014)

Section

Simposio función endotelial

License

Copyright (c) 2014 Beatriz Wills Sanín, Andrés Felipe Buitrago

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How to Cite

1.
Wills Sanín B, Buitrago AF. Implications of endothelium dysfunction in heart failure. An Fac med [Internet]. 2014 Dec. 31 [cited 2024 Jul. 17];75(4):353-9. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/10857