Urinary Excretion of 17- ketosteroids and 17-21 Dihydroxy -20- ketosteroids in Native Sea Level and Height

Authors

  • Eduardo Pretell Zárate Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

DOI:

https://doi.org/10.15381/anales.v44i3-4.6280

Abstract

We did not find differences between high altitude natives and native sea level in the urinary excretion of 17- ketosteroids and 17,21 - dihydroxy -20- ketosteroids in baseline conditions . After intravenous administration of hydrocortisone , the amount of urinary steroids appearing in the urine within 24 hours , is equal to the high altitude native and native sea level. This result is interpreted to mean that the catabolism of hydrocortisone is also similar , and that the same urinary excretion at baseline reflects equal hydrocortisone production by the adrenal cortex . By inhibiting the endogenous corticotrophin, by dexamethasone , urinary excretion of steroids in equal magnitude decreases in the two groups studied . This result is interpreted in the sense that equality in the production of hydrocortisone is intrinsically dependent on the adrenal cortex.

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Published

1961-09-25

Issue

Vol. 44 No. 3-4 (1961)

Section

Trabajos originales

License

Copyright (c) 1961 Eduardo Pretell Zárate

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How to Cite

1.
Pretell Zárate E. Urinary Excretion of 17- ketosteroids and 17-21 Dihydroxy -20- ketosteroids in Native Sea Level and Height. An Fac med [Internet]. 1961 Sep. 25 [cited 2024 Jul. 17];44(3-4):480-6. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/6280