Neurofibromatosis type 1 associated to peripheral nerve sheath and colon malignant tumor

Authors

  • Rubén Valle Médico Cirujano egresado de Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Lima, Perú.
  • Víctor Valencia Profesor de la Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Lima, Perú. Hospital Nacional Arzobispo Loayza. Lima, Perú.
  • José Huamán-Muñante Profesor de la Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Lima, Perú. Hospital Nacional Arzobispo Loayza. Lima, Perú.

DOI:

https://doi.org/10.15381/anales.v70i3.942

Keywords:

Neurofibromatosis 1, neurofibroma, sarcoma, neoplasms, colon.

Abstract

Neurofibromatosis type 1 is a dominant autosomal disease caused by mutation of the neurofibrin gene located in chromosome 17q11.2. This disease presents a variety of clinical manifestations and predisposition to develop tumors, leading to high mortality. We report the case of a patient with neurofibromatosis type 1 diagnosis who developed a malignant tumor of peripheral nerve sheath and colon cancer. The authors review the literature as well as the clinical factors, imaging and histological features associated to neurofibromas malignant transformation.

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Published

2009-09-14

Issue

Vol. 70 No. 3 (2009)

Section

Casos clínicos

License

Copyright (c) 2009 Rubén Valle, Víctor Valencia, José Huamán-Muñante

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How to Cite

1.
Valle R, Valencia V, Huamán-Muñante J. Neurofibromatosis type 1 associated to peripheral nerve sheath and colon malignant tumor. An Fac med [Internet]. 2009 Sep. 14 [cited 2024 Jul. 17];70(3):211-6. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/942