Extensive brain calcification and chorea in probable post surgical hypoparathyroidism

Authors

  • David Lira Unidad de Diagnóstico de Deterioro Cognitivo y Prevención de Demencia, Clínica Internacional. Lima, Perú. Servicio de Neurología, Clínica Internacional. Lima, Perú
  • Nilton Custodio Unidad de Diagnóstico de Deterioro Cognitivo y Prevención de Demencia, Clínica Internacional. Lima, Perú. Unidad de Investigación, Clínica Internacional. Lima, Perú. Servicio de Neurología, Clínica Internacional. Lima, Perú.
  • Rosa Montesinos Unidad de Diagnóstico de Deterioro Cognitivo y Prevención de Demencia, Clínica Internacional. Lima, Perú. Servicio de Medicina de Rehabilitación, Clínica Internacional. Lima, Perú.
  • Hernando Torres Unidad de Diagnóstico de Deterioro Cognitivo y Prevención de Demencia, Clínica Internacional. Lima, Perú. Unidad de Investigación, Clínica Internacional. Lima, Perú.

DOI:

https://doi.org/10.15381/anales.v70i2.960

Keywords:

Brain diseases, chorea, hypoparathyroidism, risperidone.

Abstract

Introduction: Cerebral calcifications may be unilateral or bilateral; unilateral etiology may include infections, trauma or stroke and bilateral may be physiologic, metabolic or idiopathic. Case report: Female 48 year-old patient who had thyroidectomy 27 years before, received levothyroxine, and who was attended for chorea, ballistic involuntary movements and progressive difficulty in walking. She presented right sided hypotonia, right upper limb winding movements, hypocalcemia, hyperphosphatemia and low parathormone levels; tomography and magnetic resonance showed bilateral calcifications in brain basal ganglia and cerebellum. She was treated with calcium citrate, calcitriol and risperidone with complete recovery. Discussion: Patients with basal ganglia calcifications have extrapyramidal symptoms (20-30%) such as parkinsonism or coreoatetosis, seizures, and neuropsychiatric disorders. Brain bilateral calcifications usually consist in calcium and other minerals deposit. Hypoparathyroidism is frequent complication of radical thyroidectomy accompanied with hypocalcemia, hyperphosphatemia and parathormone low concentration as the case described. Some patients do not develop symptoms immediately. Treatment improves symptoms but not calcifications; in our patient improvement would be due to calcium normalization more than risperidone treatment.

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Published

2009-06-15

Issue

Vol. 70 No. 2 (2009)

Section

Casos clínicos

License

Copyright (c) 2009 David Lira, Nilton Custodio, Rosa Montesinos, Hernando Torres

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How to Cite

1.
Lira D, Custodio N, Montesinos R, Torres H. Extensive brain calcification and chorea in probable post surgical hypoparathyroidism. An Fac med [Internet]. 2009 Jun. 15 [cited 2024 Jul. 17];70(2):119-22. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/960