Glucose, lactic acid and pyruvic acid at sea level and at altitude

Authors

  • Carlos Monge Cassinelli Instituto de Biología Andina, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú

DOI:

https://doi.org/10.15381/anales.v32i1.9582

Abstract

We have determined the content of glucose, lactic acid and pyruvic acid in the blood of normal subjects at sea level and on the heights of Huancayo (3.100 meters), Oroya (3.730 meters) and Morococha (4.540 meters). The group studied was moved to Huancayo Morococha where he remained 15 days; after being studied in Morococha, subjects were taken to Lima, where they were followed for 4 months. At sea level are as mean glucose, 106 mg. %; Iáctico acid, 11.48 mg. %; pyruvic acid, 37 mg 1. %. The values ​​correspond to those reported by other authors using similar methods. Studied a group of athletes on Lima had an average of 9.25 mg of lactic acid. % Lower than the total. At the height are: low blood sugar in Huancayo (64 mg%.) Oroya (78 mg%.) And Morococha (82 mg.%). The method of dosing in height is objectionable. The virtually unchanged in Huancayo lactic acid (12.76 mg.%) And Oroya (12.59 mg.%) Found in Morococha somewhat high (14.07 mg.%). The pyruvic acid unchanged in Huancayo (1 52 mg.%) Was found in Oroya frankly elevated (1.26 mg.%) And Morococha (2.13 mg.%). The group moved to Huancayo when Morococha not show obvious changes in their stockings. Going down to Lima, blood glucose was rising progressively without reaching at eight week stay, the value of the coast. Lactic acid after minor variations at eight weeks reached average Lima. The pyruvic acid down the first week below the average of Lima, and then climb high above it to the third week and eighth week and then fall to normal after 4 months of stay in Lima. The elevation of lactic acid in Morococha and pirútico acid Morococha Oroya and could be related to anoxia, before we can go further in the privacy of the phenomenon. May desglobulización phenomena may explain the elevation of pyruvic acid as acclimation phenomenon sea level. The differences in values ​​with respect to sea level figures, found at different heights, as well as variations identified during the adaptive period, show that to achieve profound biochemical changes occur acclimatization.

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Published

1949-03-14

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How to Cite

1.
Monge Cassinelli C. Glucose, lactic acid and pyruvic acid at sea level and at altitude. An Fac med [Internet]. 1949 Mar. 14 [cited 2024 Aug. 16];32(1):1-28. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/9582