Partial characterization and antimicrobial spectrum of inhibitory substances from marine Alteromonas

Authors

  • Jorge León Microbiología Ambiental y Biotecnología, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos, Lima, Perú.
  • Guillermina Tapia Laboratorio Bioquímica, Facultad de Ciencias básicas, Carrera de Bioquímica, Universidad Católica de Valparaíso, Chile.

DOI:

https://doi.org/10.15381/rpb.v6i1.8304

Keywords:

marine bacteria, inhibitory substances, extracellular substance, Alteromonas, antibiosis.

Abstract

Inhibitory substances produced by marine strains belonging to the genus Alteromonas spp. are partially characterized. Precipitation of raw extracts supernatans from strains N22.C and N11.6 with concentration saturants of ammonium sulfate and filtrates in columns Sephadex G-25 show the production of inhibitory substances (SI) of proteinacea nature. Other assays revealed that these substances have a wide spectrum of antibiotic activity against collection strains pathogens of fish, mollusks and crustaceans. Also, it shows those SI to be thermosensitive at 90 9C for 45 min and stable within the pH range of 3,0 at 9,0 for 15 min. Antibiotic activity of the substances against Vibrio angufflarum NCMB 2133, V anguillarum ATCC 19264 and Aeromonas salmonicida 76,79 was comparatively equivalent to 30 ppm of the antibiotic oxitetraciclina (OTC).

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Published

06/14/1999

Issue

Vol. 6 No. 1 (1999)

Section

Articles

License

Copyright (c) 1999 Jorge León, Guillermina Tapia

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

AUTHORS RETAIN THEIR RIGHTS:

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b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Revista Peruana de Biologia.

c. Authors retain theirs right to make a subsequent publication of their work, to use the article or any part thereof (eg a compilation of his papers, lecture notes, thesis, or a book), always indicating its initial publication in the Revista Peruana de Biologia (the originator of the work, journal, volume, number and date).

How to Cite

León, Jorge, and Guillermina Tapia. 1999. “Partial Characterization and Antimicrobial Spectrum of Inhibitory Substances from Marine Alteromonas”. Revista Peruana De Biología 6 (1): 094-103. https://doi.org/10.15381/rpb.v6i1.8304.