Antifungal effect in vitro of Origanum Vulgare in Candida Albicans strains

Authors

  • Jorge Eleodoro Villavicencio Gastelú Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Hilda Moromi Nakata Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Doris Salcedo- Moncada Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Martha Pineda-Mejía Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Donald Ramos Perfecto Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Livia Sonia Zambrano de la Peña Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Elba Estefanía Martínez Cadillo Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Gilberto Alejandro Mendoza Rojas Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Marieta Petkova-Gueorguieva Universidad Nacional Mayor de San Marcos, Facultad de Odontología
  • Roxana Margarita Bardales Álvarez Universidad Nacional San Agustín de Arequipa

DOI:

https://doi.org/10.15381/os.v19i2.12907

Keywords:

Origanum vulgare, Candida albicans,  Antifungal Agents.

Abstract

Objective: To evaluate the in vitro antimycotic effect of Origanum vulgare essential oil on Candida albi-cans strain ATCC 10231 Material and method: Selection of four different oregano geotypes was carried out, the essential oils were obtained by distillation by Drag with steam; Its quantitative chemical com-position was determined by Gas Chromatography, Mass Spectrometry (GC / MS). The antimicrotic activity of essential oils was evaluated in vitro through sensitivity tests with the disk diffusion method in agar culture against C. albicans. Results: The results showed high antimycotic activity of all oils from the concentration of 12.5%. Conclusions: Essential oils of Origanum vulgare from different geotypes show differences in their antifungal effects. The essential oil of Origanum vulgare may be is a pharmacological alternative for the treatment of fungal infections in the mouth.

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Published

2016-12-30

Issue

Section

Articles

How to Cite

1.
Villavicencio Gastelú JE, Moromi Nakata H, Salcedo- Moncada D, Pineda-Mejía M, Ramos Perfecto D, Zambrano de la Peña LS, et al. Antifungal effect in vitro of Origanum Vulgare in Candida Albicans strains. Odontol Sanmarquina [Internet]. 2016 Dec. 30 [cited 2024 Jul. 17];19(2):5-8. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/12907