USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS

Authors

  • Miguel Rodríguez Alfaro Facultad de Odontología, Universidad Nacional Mayor de San Marcos.
  • Jonny Burga Sánchez Facultad de Odontología, Universidad Nacional Mayor de San Marcos.
  • Victor Chumpitaz Cerrate Facultad de Odontología, Universidad Nacional Mayor de San Marcos.
  • Roberto Varas Hilario Facultad de Odontología, Universidad Nacional Mayor de San Marcos.
  • Roger López Bellido Facultad de Odontología, Universidad Nacional Mayor de San Marcos.
  • Vilma Chuquihuaccha Granda Facultad de Odontología, Universidad Nacional Mayor de San Marcos.
  • Juan Zegarra Cuya Facultad de Odontología, Universidad Nacional Mayor de San Marcos.

DOI:

https://doi.org/10.15381/os.v8i2.3413

Keywords:

Local anesthesia, local anestetics, antihistamines, pain tlzreshold, inflamation, infiltrative technique

Abstract

The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.

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Published

2004-12-31

Issue

Section

Articles

How to Cite

1.
Rodríguez Alfaro M, Burga Sánchez J, Chumpitaz Cerrate V, Varas Hilario R, López Bellido R, Chuquihuaccha Granda V, et al. USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALS. Odontol Sanmarquina [Internet]. 2004 Dec. 31 [cited 2024 Aug. 16];8(2):20-4. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/3413