Chemical Composition and Antibacterial Activity of Essential Oil Hyptis suaveolens (L.) Poit. (Lamiaceae) from the Venezuelan Plains

Authors

  • Nurby Ríos Tesch Departamento de Farmacognosia y Medicamentos Orgánicos. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101. Correspondencia: Facultad de Farmacia y Bioanálisis. Sector Campo de Oro, detrás del Hospital Universitario de Los Andes. IAHULA. Edif. Central, 3er piso, Mérida, República Bolivariana de Venezuela.
  • Ramón Márquez Yánez Departamento de Farmacognosia y Medicamentos Orgánicos. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.
  • Xiogelis Mendoza Rojas Departamento de Farmacognosia y Medicamentos Orgánicos. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.
  • Luis Rojas-Fermín Instituto de Investigaciones. Sección Productos Naturales. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.
  • Judith Velasco Carrillo Departamento de Microbiología y Parasitología. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.
  • Tulia Díaz Departamento de Microbiología y Parasitología. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.
  • Flor Mora Vivas Departamento de Farmacognosia y Medicamentos Orgánicos. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.
  • Carlos Yánez Colmenares Departamento de Toxicología y Farmacología. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.
  • Pablo Meléndez González Departamento de Farmacognosia y Medicamentos Orgánicos, Herbario-MERF. Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, 5101.

DOI:

https://doi.org/10.15381/rpb.v22i1.11127

Keywords:

Essential oil, Lamiaceae, antibacterial activity.

Abstract

The essential oil (EO) obtained from the leaves and flowers of Hyptis suaveolens (L.) Poit. collected from Guasdualito, Apure State, Venezuela. Oil was obtained by hydrodistillation using a Clevenger trap. The oil was analyzed by gases chromatography-mass spectrometry (GC/MS). Thirty-five compounds were identified in the leaves (91.9% of the sample) and thirty compounds in the flowers (97.0% of the sample), the major compounds: 1,8-cineole (19.1% leaves, flowers 13.3%), fenchone (18.5% leaves, flowers 16.1%), bicyclogermacrene (12.7% leaves, flowers 18.8%), D-germacrene (6.3% leaves, flowers 10.0%). The antibacterial activity was evaluated by the agar diffusion method with disks against Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, ATCC 23357 Klebsiella pneumoneae, Salmonella typhi CDC 57, Pseudomonas aeruginosa ATCC 27853. Both EO inhibited the development of E. coli, K. pneumoneae, and S. typhi, with a minimun inhibitory concentration (MIC) ranging between 300 μL/mL and 450 μL/mL. These results represent a contribution to the study of the EO of H. suaveolens, besides it the first report on the antibacterial activity of the EO obtained from flowers of this specie.

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Published

04/24/2015

Issue

Vol. 22 No. 1 (2015)

Section

Notes

License

Copyright (c) 2015 Nurby Ríos Tesch, Ramón Márquez Yánez, Xiogelis Mendoza Rojas, Luis Rojas-Fermín, Judith Velasco Carrillo, Tulia Díaz, Flor Mora Vivas, Carlos Yánez Colmenares, Pablo Meléndez González

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How to Cite

Ríos Tesch, Nurby, Ramón Márquez Yánez, Xiogelis Mendoza Rojas, Luis Rojas-Fermín, Judith Velasco Carrillo, Tulia Díaz, Flor Mora Vivas, Carlos Yánez Colmenares, and Pablo Meléndez González. 2015. “Chemical Composition and Antibacterial Activity of Essential Oil Hyptis Suaveolens (L.) Poit. (Lamiaceae) from the Venezuelan Plains”. Revista Peruana De Biología 22 (1): 103-7. https://doi.org/10.15381/rpb.v22i1.11127.