Potential use of low-NDGA Larrea divaricata extracts as antioxidant in foods

Authors

  • Sebastian Turner Turner Institute of Chemical and Metabolism of Drugs- University of Buenos Aires- National Council of Scientific and Technical Research ( IQUIMEFA-UBA-CONICET), Junín 956, University of Buenos Aires, Buenos Aires, Argentina.
  • Roberto Davicino Institute of Chemical and Metabolism of Drugs- University of Buenos Aires- National Council of Scientific and Technical Research (IQUIMEFA-UBA-CONICET), Junín 956, University of Buenos Aires, Buenos Aires, Argentina. Dr. Roberto Davicino, Immunology Unit, National University of San Luis, Ejercito de los Andes 950, San Luis-Argentina.
  • Rosario Alonso Institute of Chemical and Metabolism of Drugs- University of Buenos Aires- National Council of Scientific and Technical Research ( IQUIMEFA-UBA-CONICET), Junín 956, University of Buenos Aires, Buenos Aires, Argentina.
  • Graciela Ferraro 1 Institute of Chemical and Metabolism of Drugs- University of Buenos Aires- National Council of Scientific and Technical Research ( IQUIMEFA-UBA-CONICET), Junín 956, University of Buenos Aires, Buenos Aires, Argentina. 2 Pharmacognosy Unit, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Junín 956, Buenos Aires, Argentina.
  • Rosana Filip 1 Institute of Chemical and Metabolism of Drugs- University of Buenos Aires- National Council of Scientific and Technical Research ( IQUIMEFA-UBA-CONICET), Junín 956, University of Buenos Aires, Buenos Aires, Argentina. 2 Pharmacognosy Unit, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Junín 956, Buenos Aires, Argentina.
  • Claudia Anesini 1 Institute of Chemical and Metabolism of Drugs- University of Buenos Aires- National Council of Scientific and Technical Research ( IQUIMEFA-UBA-CONICET), Junín 956, University of Buenos Aires, Buenos Aires, Argentina. 2 Pharmacognosy Unit, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Junín 956, Buenos Aires, Argentina.

DOI:

https://doi.org/10.15381/rpb.v18i2.222

Keywords:

Nordihydroguaiaretic acid, Larrea divaricata, antioxidant activity, superoxide dismutase, catalase

Abstract

Larrea divaricata Cav. is widely distributed in Argentina. Aqueous extract, of its leaves, has documented antitumoral and immunomodulatory activities. In this study, the antioxidant activity of aqueous extract and a component, nordihydroguaiaretic acid was determined and compared using different assays. Both the aqueous extract and nordihydroguaiaretic acid exhibited antioxidant activity. However, results show that it is very likely that compounds other than nordihydroguaiaretic acid could be involved in the antioxidant activity of the extract. Since nordihydroguaiaretic acid is nephrotoxic and hepatotoxic agent, it is important to direct efforts toward the potential use of low-nordihydroguaiaretic acid L. divaricata extracts as antioxidant in foods.

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Published

08/15/2011

Issue

Vol. 18 No. 2 (2011)

Section

Articles

License

Copyright (c) 2011 Sebastian Turner Turner, Roberto Davicino, Rosario Alonso, Graciela Ferraro, Rosana Filip, Claudia Anesini

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How to Cite

Turner, Sebastian Turner, Roberto Davicino, Rosario Alonso, Graciela Ferraro, Rosana Filip, and Claudia Anesini. 2011. “Potential Use of Low-NDGA Larrea Divaricata Extracts As Antioxidant in Foods”. Revista Peruana De Biología 18 (2): 159-64. https://doi.org/10.15381/rpb.v18i2.222.