Chemical composition and antibacterial activity of the essential oil of Ambrosia peruviana Willd. from Venezuelan plains

Authors

  • Carlos A. Yánez C. Departamento de Toxicología y Farmacología. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida.
  • Nurby Rios Departamento de Farmacognosia y Medicamentos Orgánicos. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida.
  • Flor Mora Departamento de Farmacognosia y Medicamentos Orgánicos. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida.
  • Luis Rojas Instituto de investigaciones- Sección Productos Naturales. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida
  • Tulia Diaz Departamento de Microbiología y Parasitología. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida.
  • Judith Velasco Departamento de Microbiología y Parasitología. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida.
  • Nahile Rios Departamento de Toxicología y Farmacología. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida.
  • Pablo Melendez Departamento de Farmacognosia y Medicamentos Orgánicos. Facultad de Farmacia y Bioanálisis. Universidad de los Andes, Mérida.

DOI:

https://doi.org/10.15381/rpb.v18i2.245

Keywords:

Ambrosia peruviana, essential oil, antibacterial activity.

Abstract

In Venezuela, are currently exploring new sources of natural antibacterial agents, due to increased bacterial resistance, including essential oils derived from plants. For this reason in the present study we determined the chemical composition of essential oil obtained from leaves collected on Ambrosia peruviana Willd Guasdualito, Apure State, Venezuela. The volatile compounds were isolated by hydrodistillation in a Clevenger trap and then subjected to qualitative analysis and quantitative by gas chromatography-mass spectrometry (GC / MS) on an HP GC-MS System, model 5973, finding as the major compound gamma-curcumeno (23.99%) followed by curcumeno-ar (14.08%), bornyl acetate (10.35%), camphor (5.03%) and epoxide oximene (4.79%). The antibacterial activity of essential oil by the agar diffusion method with discs against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi and Pseudomonas aeruginosa showed activity against S. aureus, E. faecalis, E. coli and S. Typhi, with MIC values of 350-500 micrograms/ mL. This research represents the first report of antibacterial activity of A. peruviana.

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Published

08/15/2011

Issue

Vol. 18 No. 2 (2011)

Section

Articles

License

Copyright (c) 2011 Carlos A. Yánez C., Nurby Rios, Flor Mora, Luis Rojas, Tulia Diaz, Judith Velasco, Nahile Rios, Pablo Melendez

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How to Cite

Yánez C., Carlos A., Nurby Rios, Flor Mora, Luis Rojas, Tulia Diaz, Judith Velasco, Nahile Rios, and Pablo Melendez. 2011. “Chemical Composition and Antibacterial Activity of the Essential Oil of Ambrosia Peruviana Willd. From Venezuelan Plains”. Revista Peruana De Biología 18 (2): 149-51. https://doi.org/10.15381/rpb.v18i2.245.