Protein profile of whole saliva of partial and complete edentulous patients

Authors

  • Rolando Pablo Juárez Universidad Nacional del Nordeste, Facultad de Odontología, Corrientes, Argentina https://orcid.org/0000-0001-8950-3373
  • Claudia Patricia Serrano Universidad Nacional del Nordeste, Facultad de Ciencias Exactas y Naturales y Agrimensura (Departamento de Bioquímica), Corrientes, Argentina https://orcid.org/0000-0003-4988-6677
  • Gabriela Noemí Gómez Universidad Nacional del Nordeste, Facultad de Ciencias Exactas y Naturales y Agrimensura (Departamento de Bioquímica), Corrientes, Argentina https://orcid.org/0000-0001-8918-8174

DOI:

https://doi.org/10.15381/os.v25i4.22118

Keywords:

Jaw edentulous, Salivary proteins and peptides, Adult

Abstract

Objective. Aim of this study was to characterize the protein profile of whole saliva in partial and complete edentulous and determine the changes in salivary protein expression of adults with varying degrees of tooth loss. Methods. In this observational study, unstimulated saliva samples were collected from 80 adults (age 18-73 years), 20 dentulous and 60 edentulous. Partial and complete edentulous patients (EP) were divided into three groups with different number of teeth lost. Concentration and electrophoretic profile (cellulose acetate membrane and polyacrylamide gels) of the salivary proteins were compared between the groups. Results. Total protein and albumin concentration was highest in the group of dentulous patients (DP) and significantly different in PE groups (p<0.0001). A significant difference (p<0.011) was observed in the gamma globulin fraction between PD versus PE and in the electrophoretic profile of salivary proteins between the different groups. A high number of 66 kDa bands was founded in all groups (p=0.049). Conclusions. The concentration and electrophoretic profile of the salivary proteins of DP and EP were different.

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Author Biographies

  • Rolando Pablo Juárez, Universidad Nacional del Nordeste, Facultad de Odontología, Corrientes, Argentina

    Doctor en Odontología.

  • Claudia Patricia Serrano, Universidad Nacional del Nordeste, Facultad de Ciencias Exactas y Naturales y Agrimensura (Departamento de Bioquímica), Corrientes, Argentina

    Especialista en Hematología.

  • Gabriela Noemí Gómez, Universidad Nacional del Nordeste, Facultad de Ciencias Exactas y Naturales y Agrimensura (Departamento de Bioquímica), Corrientes, Argentina

    Doctora en Química.

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Published

2022-10-21

Issue

Vol. 25 No. 4 (2022)

Section

Articles

License

Copyright (c) 2022 Rolando Pablo Juárez, Claudia Patricia Serrano, Gabriela Noemí Gómez

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

AUTHORS RETAIN THEIR RIGHTS:

a. Authors retain their trade mark rights and patent, and also on any process or procedure described in the article.

b. Authors retain their right to share, copy, distribute, perform and publicly communicate their article (eg, to place their article in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in the Odontología Sanmarquina.

c. Authors retain theirs right to make a subsequent publication of their work, to use the article or any part thereof (eg a compilation of his papers, lecture notes, thesis, or a book), always indicating the source of publication (the originator of the work, journal, volume, number and date).

How to Cite

1.
Juárez RP, Serrano CP, Gómez GN. Protein profile of whole saliva of partial and complete edentulous patients. Odontol Sanmarquina [Internet]. 2022 Oct. 21 [cited 2024 Jul. 17];25(4):e22118. Available from: https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/22118